Product Description

Ingredients & Composition:

Ketoconazole IP 2% w/v,
Chlorhexidine gluconate IP 4% w/v
Medicated shampoo base q.s

Description / Action: 

Dermotil-K shampoo is a specially formulated Anti-fungal and Anti-bacterial Shampoo for treating Fungal and associated secondary bacterial skin infections.

Pharmacodynamics:

Ketoconazole interacts with 14-alpha-lanosterol demethylase, a cytochrome P-450 enzyme necessary for the conversion of lanosterol to ergosterol. This results in inhibition of ergosterol synthesis and increased fungal cellular permeability which leads to fungal cell death and prevents further multiplication.

The positively charged chlorhexidine molecule reacts with negatively charged phosphate groups on microbial cell surfaces – this reaction both destroys the integrity of the cell, allowing leakage of intracellular material, and allows chlorhexidine to enter the cell, causing precipitation of cytoplasmic components leading to bacterial death and prevents bacterial multiplication.

Class: Medicated Shampoo (Antiseptic / Antifungal)

Indication / Usage/ Benefits:

To treat & control dermatophyte infections like Ringworm caused by Microsporum canis.

Bacterial infections of skin like pyoderma caused by Staphylococcus intermedius.

Additional Information